Synergy Between GLP-1 Receptor Agonists, Nutritional Therapy, and Physical Exercise in Optimising Body Composition and Cardiometabolic Health
DOI:
https://doi.org/10.36557/2674-9432.2026v5n1p2201-2205Palavras-chave:
GLP-1, Weight Loss, Sarcopenia.Resumo
Therapy with glucagon-like peptide-1 (GLP-1) receptor agonists has revolutionized the treatment of obesity and metabolic dysfunctions. However, the rapid weight loss induced by these drugs raises clinical concerns regarding depletion of fat-free mass and reductions in bone mineral density. This short communication synthesizes the recent literature on the physiology of GLP-1 receptor agonists, highlighting the non-negotiable need for multidisciplinary interventions. The integration of appropriate nutritional management with periodized resistance training emerges as the gold standard to mitigate the risk of secondary sarcopenia and to potentiate systemic adaptations to treatment.
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Copyright (c) 2026 Rodolfo Melo Raiol

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