TRANSTORNO COMPORTAMENTAL DO SONO REM: ABORDAGENS TERAPÊUTICAS EMERGENTES
DOI:
https://doi.org/10.36557/pbpc.v3i2.116Keywords:
REM sleep behavior disorder, REMSD, treatmentAbstract
Introduction: Rapid Emerging Respiratory Behavior Disorder (REMBD) is a parasomnia characterized by the absence of normal muscle atonia during REM sleep, resulting in complex and vivid motor behaviors, often associated with dreams. Methods: This is an integrative review conducted through the Scopus, PubMed® and SciELO databases, using the descriptors REM sleep behavioral disorder, REMBD and treatment. Studies published in the last 13 years, in English, Spanish or Portuguese, that addressed the topic were included. Results and discussions: The treatment of REMBD includes environmental safety measures and the suspension of certain medications and alcohol. Clonazepam and melatonin are the main drugs used, with melatonin being preferred due to its mild adverse effects. Other options, such as rivastigmine and memantine, are used when necessary. The approach should be personalized, considering efficacy and tolerability. Conclusion: The therapeutic approach to REMBD should be carefully individualized to meet the specific needs of each patient. It is essential to consider the effectiveness of the proposed treatments, evaluating which medications or combinations of medications provide the greatest relief of symptoms with the least adverse effects. The tolerability of treatments is equally important, since patients may react differently to different therapies and may have specific limitations or contraindications.
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Copyright (c) 2024 Jamilton Jesus Santos Junior , Lorena Gabryelly da Silva Alves , Edney Marcelo de Melo Aragão Júnior , Rinaldo Rocha de Lucena Filho , Paulo Sérgio de Souza Larrea , Rhayran Espindola Rodrigues , Julianna Miranda Gomes , Amanda Virgínia Oliveira Leite , Leonardo Mota Silva, Markos Paulo Alves Ferreira, Martha de Araujo Medeiros Pereira , Lucas Gabriel Lopes Donato , Ernesto Brandão de Albuquerque Maranhão

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