BENEFITS OF EARLY THROMBOLYSIS IN THE MANAGEMENT OF PULMONARY THROMBOEMBOLISM: A LITERATURE REVIEW
DOI:
https://doi.org/10.36557/pbpc.v3i2.240Keywords:
Pulmonary Embolism, Pulmonary Thromboembolism, Thrombolytic Agents, Thrombolytic TherapyAbstract
Pulmonary thromboembolism, or PTE, is a pulmonary disorder caused by obstruction of the pulmonary artery by thrombi originating mainly from previous events of deep vein thrombosis in the lower limbs. This condition has a high rate of associated morbidity and mortality, leading to death in more serious cases. In view of this, considering the severity of PTE and the high mortality associated with it, as well as the high costs to the health system as a result of expensive rehabilitation treatment, this study is justified. Its aim is to evaluate the benefits of early thrombolysis in the management of PTE, understanding its role in improving the prognosis and clinical outcome of patients. The study was based on a literature review using articles in English and Portuguese published over the last 32 years in reference databases such as SciELO and PubMed. Analysis of the articles collected showed that thrombolysis plays a crucial role in the management of pulmonary thromboembolism, together with full anticoagulation, highlighting the importance of screening and immediate diagnosis in the emergency or intensive care setting. This measure can be instituted up to the 14th day of symptom onset, preferably in the first 12 to 24 hours, and is linked to a reduction in negative outcomes, improved prognosis and shorter hospital stays. Thus, the present evidence supports the need for protocols that emphasize early thrombolysis as a crucial and indispensable intervention for reducing mortality, as well as promoting a more efficient and safer recovery for patients.
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Copyright (c) 2024 Rayssa Almeida Nogueira, Maria Eduarda Miniño Ferrari, Vinícius Rodrigues Mendonça, Nicole Almeida Ramos Jaegge, Robison Antônio Coelho Junior, Núbia Marques Pacheco, Eustáquio Moreira Oliveira Filho, Otavio Soares Torezani, Arthur Vasconcellos Reinoso, Juliana Quintanilha Schuabb, Alexia Fernanda de Souza Ribeiro Vieira
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