PAPEL DA SARCOPENIA COMO PREDITOR DE MORTALIDADE EM PACIENTES GRAVES: O QUE DIZ A LITERATURA
DOI:
https://doi.org/10.36557/pbpc.v4i1.314Keywords:
Sarcopenia, Mortalidade, Cuidado Intensivo, Fatores PrecipitantesAbstract
Introduction: Sarcopenia, characterized by the progressive and generalized loss of muscle mass, strength, and function, is a multifactorial condition that primarily affects the elderly but can also occur in younger individuals under conditions of intense metabolic stress, such as critical illnesses, systemic inflammation, and prolonged immobility. In recent years, a growing body of evidence has pointed to a direct association between sarcopenia and adverse clinical outcomes in critically ill patients. Therefore, this article reviews the existing literature on the topic, aiming to evaluate the correlation between sarcopenia and negative outcomes, including mortality, in critically ill patients, while highlighting the underlying mechanisms and clinical implications. Methodology: This is an integrative review on the proposed topic, based on full-text scientific articles in Portuguese or English, retrieved from databases such as PubMed, SciELO, the Virtual Health Library, and others, within the time frame of 2010 to 2024. Health Sciences Descriptors (DeCS) were used to select the studies most relevant to the research. Results and Discussion: The literature review revealed consistent evidence that sarcopenia is an independent predictor of mortality in critically ill patients, particularly in populations admitted to intensive care units (ICUs). The included studies emphasize the importance of early assessment of sarcopenia as part of clinical management, as well as the association between reduced skeletal muscle mass and adverse outcomes such as hospital mortality, prolonged length of stay, and increased postoperative complications. Conclusion: The findings of this review suggest that the identification and management of sarcopenia should be incorporated into routine practices in critical care settings. In this context, future strategies should focus on developing accessible and standardized tools for sarcopenia assessment, in addition to studies investigating specific interventions for high-risk populations.
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Copyright (c) 2025 Vanessa Magalhães, Igor Menescal Jales, Débora Yane Oliveira de Medeiros, Yasmin Lima de Farias Cavalcante, Allan Michel Bezerra Lima, Priscila Barbosa Tabuso Fiuza, Renata Silveira Maciel, Maíra Dias de Oliveira Campos, Fernanda Queiroz Rêgo, Thais Mendonça da Costa, Marília Cristina Gomes de Lima, Patricia Assis Frota, Renata Dantas Amorim Rosado, Maria Mauricélia Lopes de Almeida, Alessandra Sousa Celestino de Paula Lima
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