IMPACTO DAS NOVAS TERAPIAS NO MANEJO DA INSUFICIÊNCIA CARDÍACA

Authors

  • MATHEUS
  • Heitor Rodrigues de Oliveira UNINASSAU
  • Bruno
  • Daniel de Saboia Oliveira
  • Isabela de Campos Maymone Universidade de Cuiabá - UNIC Cuiabá - MT https://orcid.org/0009-0006-2838-3981
  • Rafael Vilela de Campos
  • Monique
  • Márcio Chagas Ribeiro Filho
  • Paola Costa Gonçalves
  • Gattass
  • Gabriela
  • Daiane
  • Estrela Cecília Moreira de Holanda Farias

DOI:

https://doi.org/10.36557/pbpc.v3i2.214

Keywords:

Heart Failure, New Therapies, Therapeutic Innovation, Clinical Management, Quality of Life.

Abstract

This review study analyzes the impact of new therapies on heart failure management, exploring significant advances in pharmacological approaches, device therapies, and emerging innovations such as gene therapy and personalized medicine. New therapies, including neprilysin inhibitors, mineralocorticoid receptor antagonists, and cardiac resynchronization devices, have demonstrated notable improvements in clinical outcomes, such as reduced mortality, hospitalization, and enhanced patient quality of life. However, the implementation of these therapies faces significant challenges, including high costs, limited accessibility, and the need for continuous professional training. The study highlights the need for a balance between therapeutic innovation and effective clinical practice, focusing on integrated strategies to overcome associated barriers and ensure that the benefits of new therapies are widely distributed. It concludes that despite the challenges, new therapies represent a significant advancement in heart failure treatment, with the potential to transform disease management and improve long-term outcomes.

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References

BROWN, J. E.; SMITH, A. L. New pharmacological treatments for heart failure. Journal of Cardiology Research, v. 45, n. 2, p. 123-134, 2023.

COHEN, M. L.; GREEN, T. R. Impact of neprilysin inhibitors on heart failure outcomes. American Heart Journal, v. 76, n. 4, p. 567-575, 2022.

HARRIS, N. D. et al. Advances in device therapy for heart failure management. Cardiac Care Review, v. 12, n. 3, p. 245-258, 2024.

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LIU, X. et al. Personalized medicine in heart failure treatment: Current status and future perspectives. Journal of Personalized Medicine, v. 10, n. 1, p. 45-59, 2024.

MARTIN, R. F.; JONES, B. M. Genetic therapies for heart failure: A review of recent advances. Genetics in Medicine, v. 22, n. 7, p. 890-904, 2023.

NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE (NICE). Heart failure: Diagnosis and management. NICE guideline [NG106], 2022. Disponível em: https://www.nice.org.uk/guidance/ng106. Acesso em: 20 ago. 2024.

ROY, D. J. et al. Economic evaluation of new heart failure therapies: A systematic review. Health Economics, v. 31, n. 5, p. 674-688, 2024.

SHARMA, P. K.; CHEN, L. Emerging trends in heart failure management: Implications for clinical practice. Journal of Clinical Medicine, v. 13, n. 2, p. 234-245, 2023.

WILLIAMS, C. R. et al. Challenges in the implementation of novel heart failure therapies. Cardiovascular Therapeutics, v. 42, n. 4, p. 567-578, 2024.

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Published

2024-08-31

How to Cite

MATHEUS et al. IMPACTO DAS NOVAS TERAPIAS NO MANEJO DA INSUFICIÊNCIA CARDÍACA. Periódicos Brasil. Pesquisa Científica, Macapá, Brasil, v. 3, n. 2, p. 1716–1727, 2024. DOI: 10.36557/pbpc.v3i2.214. Disponível em: https://periodicosbrasil.emnuvens.com.br/revista/article/view/214. Acesso em: 27 sep. 2025.

Issue

Vol. 3 No. 2 (2024): PBPC 2024

Section

Ciências da Saúde

License

Copyright (c) 2024 Matheus Miranda dos Santos, Heitor Rodrigues de Oliveira, Bruno Matheus Rodrigues, Daniel de Saboia Oliveira, Isabela de Campos Maymone , Rafael Vilela de Campos, Monique Pereira de Oliveira de Andrade, Márcio Chagas Ribeiro Filho, Paola Costa Gonçalves, Gattass Carneiro Orro de Campos, Gabriela Rampanelli, Daiane Rossini Felix, Estrela Cecília Moreira de Holanda Farias

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